The Marches is probably one of the safest Italian regions. There is very little violent or petty crime, even in major cities like Ancona. The family-oriented vibe of the Marches has led to a sense of community, and as a result most residents are highly respectful and friendly of each other and of you, even after a few drinks (and as long as you don’t antagonise them). People here might be more reserved than other Italian regions especially in the inland villages. Despite being a very ‘rural’ region of Italy, the towns and villages are an almost bizarrely short distance from each other, even in awkwardly hilly areas; if you get lost you’ll only have to walk about 20 minutes at the absolute maximum until you come across a couple of houses (or even a town with a shop, post office and such). Because of the undulating terrain, it’s also very easy to locate the next town visually as most of them are perched on hilltops, and as a result it’s unlikely Le Marche will ever leave you feeling truly isolated.
Your only trouble in this quiet region, if you have any, is that the parts of the Marches dominated by wilderness and not settlements are pretty remote. If your car breaks down or you get lost up in the Sibillini, there is a slim possibility you will find yourself an insurmountable distance from the nearest help, and emergency services may need to be contacted. However, this is highly, highly unlikely; the mountains are dotted with people at all times of the year and the refuge points are easily navigable on foot with good preparation and a map.
